Altered granite occurrences (G(Ⅱ) and GV) at Gabal (G.) Gattar are the most important mineralized rocks hosting U-mineralization in Egypt.This mineralized granite is affected by multi-stage hydrothermal alteration processes along brittle structures.This alteration comprises pre-ore alkali-metasomatism and ore-stage hydrothermal hematitization,silicification,kaolinitization,fluoritization,carbonatization and episyenitization.Autoradiographic examination indicates that primary uranium mineralization is present as massive or disseminated ores along tectonic fractures,interstitially in granular minerals,and as cements of breccias.Uraninite,pitchblende and coffinite are the main primary minerals,while uranophane and kasolite are the secondary ones.Galena,chalcopyrite,pyrrohtite and pyrite are the most abundant sulphides in association with uranium mineralizations.Hydrothermal alterations at the GⅡ occurrence exhibit an increase in Ni,Cu,Zn,Pb,Mo,Nb,Rb beside HREEs and a decrease in Ba,Co,Sr,and (V),while alterations at the GV occurrence show enrichment in Ni,Cu,Pb,Mo,Nb,Y,HREEs and depletion in Zn,Ba,Co,Rb,Sr,and (V).Hydrothermal alteration during the late magmatic stage is also identified through the development of unusual REE patterns and fractionation of ratios like Zr/Hf and Y/Ho out of the CHARAC (Charge Radius Controlled) range.Non-chondritic Y/Ho ratio at GV is of larger value than chondritic one which may result from water-rock interaction or print from the encompassing sedimentary rocks.Fluid inclusion studies on quartz and fluorite revealed that temperatures of the mineralizing fluids range between 126 and 240℃ at pressure ≤0.5×108 Pa and give salinity values ranging between 1 wt％ and 7.8 wt％ NaCl equivalent.