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采用五种免疫功能测定法对８３２只健康ＫＭ小鼠和８３只ＢＡＬＢ／ｃ小鼠进行免疫学功能指标的测定。结果表明ＣｏｎＡ诱导小鼠脾淋巴细胞转化能力ＯＤ值分别为００１４８～００１９２和００１２０１～００２０６；二硝基氟苯诱导小鼠迟发型变态反应（耳肿胀法）小鼠耳重差分别为１０３９～１２１７ｍｇ和１１４６８～１６２３４ｍｇ；血清溶血素抗体积数分别为７８９８～９１３０和１０６７３～１１６０７；碳廓清吞噬指数ａ分别为４７５２～４８５８和４４７０～５５９８；小鼠巨噬细胞吞噬鸡红细胞的指数分别为０３９８～０４６１和０３３１～０４９９，吞噬百分数分别为３３７２～３７１８和２９２４～４１１０。上述数据可信区间为９９％，两鼠间ＤＴＨ及抗体积数值有高度显著性差异（Ｐ＜００１）。在进行免疫药理学、免疫毒理学和保健食品功能学研究时，以实验小鼠为材料运用ＤＴＨ和血清溶血素抗体积数实验时，应首选ＢＡＬＢ／ｃ小鼠。而进行其它三项免疫学指标实验时可首选ＫＭ小鼠。
Five immunological assays were used to determine the immunological parameters of 832 healthy KM mice and 83 BALB / c mice. The results showed that ConA-induced mouse spleen lymphocyte transformation ability OD values were 0 0148 ~ 0 0192 and 0 01201 ~ 0 0 206; dinitrofluorobenzene-induced mouse delayed-type hypersensitivity (ear swelling) mice Ear weight difference were 10 39 ~ 12 17mg and 11 468 ~ 16 234mg; serum hemolysin antibody volume were 78 98 ~ 91 30 and 106 73 ~ 116 07; carbon clearance phagocytic index a Respectively, 4752 ~ 4858 and 4470 ~ 5598; mouse macrophage phagocytosis chicken erythrocytes index were 0 398 ~ 0 461 and 0 331 ~ 0 499, phagocytic percentage were 33 72 ~ 37 18 and 29 24 ~ 41 10. The confidence interval of the above data was 99%. There was a highly significant difference between the DTH and anti-volume values between the two mice (P <001). In immunopharmacology, immunotoxicology and health food functional studies, the use of experimental mice as the material DTH and serum hemolysin antibody volume should be the first choice of BALB / c mice. The other three immunological indicators of experiments KM mice may be the first choice.