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电镜观察42例急性缺血性脑卒中、20例高血压及20名健康成人的血小板聚集物(％)和每一聚集物内的血小板个数。结果急性缺血性脑卒中组分别为31.06±13.54和128.95±67.02,高血压组分别为16.18±7.89和50.70±28.68,健康人组分别为5.93±3.10和16.20±8.35,三组相比有显著差异。但在急性缺血性脑卒中病例中,脑血栓与TIA相比,无明显差异。认为血小板聚集性增高是急性缺血性脑卒中发病的重要因素,尤以长期高血压患者,如血小板聚集性增高,可作为脑血栓及TIA的危险信号。
Electron microscopic observation of 42 cases of acute ischemic stroke, 20 cases of hypertension and 20 healthy adults platelet aggregation (%) and the number of platelets within each aggregate. Results The percentages of acute ischemic stroke were 31.06 ± 13.54 and 128.95 ± 67.02 respectively, while those in hypertension group were 16.18 ± 7.89 and 50.70 ± 28.68, respectively, and those in healthy group were 5.93 ± 3.10 and 16.20 ± 8.35 respectively difference. However, in the case of acute ischemic stroke, there was no significant difference in cerebral thrombosis compared with TIA. That platelet aggregation is an important factor in the pathogenesis of acute ischemic stroke, especially in patients with long-term hypertension, such as increased platelet aggregation can be used as a risk signal for cerebral thrombosis and TIA.