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目的研究分析C反应蛋白(CRP)和和脂蛋白[Lp(a)]的检测结果对急性脑梗塞患者发病及其变化过程的诊断意义。方法分别检测35例急性脑梗塞患者(观察组)治疗前后以及35例正常人(对照组)的CRP和Lp(a)水平。结果急性脑梗塞患者治疗前后的CRP和Lp(a)检测结果都明显高于对照组,差异有统计学意义(P<0.05);CRP检测值在急性脑梗塞患者的治疗前后对比,前者的数值更高,差异也有统计学意义(P<0.05);而Lp(a)在治疗前后的检测值则无明显变化,差异无统计学意义(P>0.05)。结论血清中Lp(a)浓度过高容易增加脑血管疾病的发病率,急性脑梗塞患者的CRP血清浓度较正常人明显升高,而且其值得高低与疾病的严重程度成比例增长。所以,CRP和Lp(a)的结果对急性脑梗塞的诊断与病情进展的观察具有重要的意义。
Objective To study the diagnostic value of the detection of C-reactive protein (CRP) and lipoprotein (Lp (a)] in the pathogenesis of acute cerebral infarction and its changes. Methods The levels of CRP and Lp (a) were measured in 35 patients with acute cerebral infarction (observation group) before and after treatment and 35 normal persons (control group) respectively. Results The results of CRP and Lp (a) before and after treatment in patients with acute cerebral infarction were significantly higher than those in the control group (P <0.05). The CRP values in patients with acute cerebral infarction before and after treatment were compared, the former (P <0.05). However, there was no significant difference in Lp (a) before and after treatment, the difference was not statistically significant (P> 0.05). Conclusion The high concentration of Lp (a) in serum may increase the incidence of cerebrovascular diseases. The concentration of CRP in patients with acute cerebral infarction is significantly higher than that in normal people, and its value is proportional to the severity of the disease. Therefore, the results of CRP and Lp (a) are of great significance for the diagnosis of acute cerebral infarction and the progress of the disease.