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近红外光在脂肪乳和葡萄糖混合溶液介质中传播,在介质表面形成漫反射光,稳态情况下,检测位置处检测的漫反射光包含了全部的弹道光、蛇行光与漫散射光,其中部分弹道光和漫散射光降低了葡萄糖浓度的检测精度。通过蒙特卡洛模拟方法分别对10%和3%的intralipid-葡萄糖溶液进行时域模拟,分析统计不同检测位置漫反射光的不同光程组成,对时间扩展曲线的峰值时间与平均飞行时间范围内的漫反射光子进行检测能够提高浮动基准位置即漫反射光强度对葡萄糖浓度最不灵敏的检测位置的检测精度,同时,这部分光子在漫反射光强的极大值处提高了漫反射光强与葡萄糖浓度的线性相关系数,抽取这部分光程的漫反射光在极大值位置提升了对葡萄糖浓度的检测灵敏度。
The near-infrared light propagates in the medium of the mixed solution of fat emulsion and glucose to form diffuse reflection light on the surface of the medium. In steady state, the diffuse reflection light detected at the detection position contains all the ballistic light, the meandering light and the diffuse scattering light, wherein Partially ballistic and diffusely scattered light reduce the detection accuracy of glucose concentration. The time-domain simulations of 10% and 3% intralipid-glucose solutions were carried out by Monte-Carlo simulation. The different optical path lengths of diffusely reflected light at different detection positions were analyzed. The peak time of the extended time curve was compared with the average flight time Of diffuse photons detected can improve the detection accuracy of the floating reference position, that is, the position where the diffuse reflection light intensity is the most insensitive to glucose concentration. At the same time, this part of photons increases the diffuse reflection intensity at the maximum of diffuse reflection intensity The linear correlation coefficient with glucose concentration, extracted this part of the diffuse light path at the maximum position to enhance the detection sensitivity of glucose concentration.