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美《临床和实验科学年报》第10卷第3期(1980年)报道:在过去的9年,已采用二种重要的方法辨别正常和恶性淋巴细胞的细胞表面特征。正常的成熟T-细胞有羊红细胞(E~+)受体,而成熟的B细胞带有膜-结合的免疫球蛋白分子(SIg~+)。以上所见可将小儿急性淋巴细胞白血病区分为3种主要类型:(1)B-细胞白血病(SIg~+E-);此型少见(大约2％),预后最差。(2)T-细胞白血病(SIg~-,E~+);
The American Society for Clinical and Experimental Science Volume 10, Number 3 (1980) reports that in the past nine years, two important approaches have been employed to distinguish the cell surface features of normal and malignant lymphocytes. Normal mature T-cells have sheep erythrocyte (E ~) receptors, while mature B cells carry membrane-bound immunoglobulin molecules (SIg ~ +). The above findings can be divided into three main types of pediatric acute lymphoblastic leukemia: (1) B-cell leukemia (SIg ~ + E-); this rare type (about 2%), the worst prognosis. (2) T-cell leukemia (SIg ~ -, E ~ +);