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叶酸(FA)和维生素B_(12)(B_(12))是DNA 合成的必须物质,其代谢紊乱或缺乏则DNA 的合成发生障碍,影响造血细胞在骨髓的增殖.有关它与尿毒症的关系,尚少见系统报道.我们自1988年以来,对尿毒症患者、透析患者(腹透和血透)应用促红细胞生成素(EPO)前后FA、B_(12)的变化进行了临床观察,现报告如下.
Folic acid (FA) and vitamin B 12 (B 12) are necessary materials for DNA synthesis, and their metabolic disorders or lack of DNA impair the synthesis of DNA and affect the proliferation of hematopoietic cells in the bone marrow. , It is seldom reported in the system.We have observed the changes of FA and B 12 before and after the application of EPO in patients with uremia and dialysis (dialysis and hemodialysis) as follows.