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鉴于节律不整患者为数不少,而且目前常用的抗节律不整药奴佛卡因胺仍非最理想,因此,寻找新的抗节律不整药,是一个极为迫切的課題。根据(?)等观察,奴佛卡因胺仅对心室性节律不整效果較好,而对心房性节律不整,尤其是带有頑固性顫动的病人,疗效极差。同时,奴佛卡因胺还有許多全身性副作用。近年来,苏联学者合成了新的抗节律不整药——巴斯卡因(?),它是一分子羥基奴佛卡因胺和一分子对氨基水楊酸的复合物,呈白色結晶性粉末,易溶于水,結构式如下:
In view of the large number of patients with irregular rhythm, and currently commonly used anti-irregular drug Novocaine amine is still not the most ideal, therefore, to find new anti-rhythm irregular drug is an extremely urgent issue. According to (?) And other observations, novermectin amine ventricular rhythm dysfunction better, and atrial rhythm irregularities, especially with refractory tremor in patients with poor efficacy. At the same time, there are many systemic side effects of novocaline. In recent years, Soviet academics have synthesized a new anti-rhythmic drug - baicalin (?), Which is a molecule of hydroxyfreeflyine and a molecule of amino acid salicylic acid complex, was white crystalline powder , Soluble in water, the structural formula is as follows: