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目的:观察胺碘酮联合美托洛尔(倍他乐克)治疗急性心肌梗死(AMI)伴快速房颤的临床疗效。方法:60例AMI患者伴快速房颤,给予胺碘酮首剂150mg静脉推注,15min后未转复窦性心律,可再给以150mg静推,继之0.5～1.0mg·min-1持续静滴1～3d,静脉用药同时给予口服胺碘酮(第1周200mg,tid,第2周200mg,bid,第3周200mg,qd,24h总量<1200mg)和倍他乐克(25～50mg,bid),观察用药前后房颤转复、心率、血压变化情况。结果:55例房颤转复,所有患者心室率得到控制,用药前后血压平稳。结论:胺碘酮联合美托洛尔治疗急性心肌梗死伴快速房颤安全有效。
Objective: To observe the clinical efficacy of amiodarone combined with metoprolol (metoprolol) in the treatment of acute myocardial infarction (AMI) with rapid atrial fibrillation. Methods: Sixty AMI patients with rapid atrial fibrillation were given intravenous injection of amiodarone 150mg intravenously. After 15min, sinus rhythm was not reversed and 150mg intravenous bolus followed by 0.5-1.0mg · min-1 Intravenous administration of intravenous amiodarone (first week 200mg, tid, the first two weeks 200mg, bid, the first three weeks 200mg, qd, 24h total <1200mg) and metoprolol (25 ~ 50mg, bid), observed before and after treatment of atrial fibrillation, heart rate, blood pressure changes. Results: 55 cases of atrial fibrillation, all patients ventricular rate was controlled before and after treatment, blood pressure was stable. Conclusion: Amiodarone combined with metoprolol in the treatment of acute myocardial infarction with rapid atrial fibrillation is safe and effective.