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对339例住院分娩新生儿及其父母和1656例非肝病患儿进行了血清乙肝五项(HBVM)和抗-HCV测定。发现产妇感染乙肝病毒(HBV)及HBeAg、HBsAg阳性者致胎儿宫内感染的危险性最大,其中5例“大三阳”产妇所生婴儿中有4例(80%)HBsAg阳性;3例父亲和2例婴儿HBsAg阳性者中,有2例父亲和1例婴儿HVB-DNA阳性。非肝病患儿HBV感染率达24.1%,其HBsAg阳性率随年龄增长而增高,抗-HBs阳性率则随年龄增长而逐渐降低。新生儿抗-HCV阳性率为0%,而非肝炎患儿则为1.5%。
Serum HBVM and anti-HCV were measured in 339 newborns with hospital delivery and their parents and 1656 children with non-liver disease. Found that maternal infection with hepatitis B virus (HBV) and HBeAg, HBsAg-positive fetal infection caused by the highest risk of intrauterine infection, of which 5 cases of “big three positive” mothers born in 4 (80%) HBsAg positive mothers; 3 fathers Two of the two HBsAg positive infants were positive for HVB-DNA in two of their fathers and one infantile. The HBV infection rate of non-liver disease children was 24.1%, the positive rate of HBsAg increased with age, the positive rate of anti-HBs gradually decreased with age. Neonatal anti-HCV positive rate was 0%, while non-hepatitis children was 1.5%.