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目的 探讨研究矽肺结核及矽肺患者结核分支杆菌L型致病情况的价值。方法 对矽肺结核组和矽肺组患者 ,分别进行痰结核分支杆菌和痰结核分支杆菌L型培养 ,并对结果进行对照观察。结果 矽肺结核组 6 0例痰结核分支杆菌培养阳性 6例 ,阳性率 10 %(同时出现结核分支杆菌L型培养阳性 5例 ,占 83 %) ;痰结核分支杆菌L型培养阳性 2 8例 (其中Ⅰ期矽肺结核L型菌检出率为33 %、Ⅱ期为 6 7%、Ⅲ期 10 0 %) ,阳性率 47%(P <0 0 1) ;矽肺组 30例无一例结核分支杆菌阳性 ,结核分支杆菌L型阳性 3例 ,占 10 %。结论 结核分支杆菌L型培养方便快速 ,能提高结核分支杆菌的检出率 ,对矽肺结核的早期诊断及减少矽肺结核复发的漏、误诊有肯定的价值 ;随着矽肺期别的上升 ,结核分支杆菌L型的检出率明显增高
Objective To investigate the value of the pathogenicity of Mycobacterium tuberculosis in patients with silicosis and silicosis. Methods The patients with silicotic pulmonary tuberculosis and silicosis were treated with sputum Mycobacterium tuberculosis and sputum Mycobacterium tuberculosis L-type culture, and the results were compared with the control. Results Sixty cases of sputum Mycobacterium tuberculosis in silicosis group were positive in 6 cases, the positive rate was 10% (5 cases of Mycobacterium tuberculosis L type culture were positive at the same time, accounting for 83%). Positive sputum Mycobacterium tuberculosis L-type culture was positive in 28 cases Among them, the detection rate of stage L silicosis was 33%, 67% in stage Ⅱ, 100% in stage Ⅲ), and the positive rate was 47% (P <0.01). None of the 30 cases in silicosis group were Mycobacterium tuberculosis Positive, Mycobacterium tuberculosis L-positive in 3 cases, accounting for 10%. Conclusion Mycobacterium tuberculosis L-type culture is convenient and rapid, which can improve the detection rate of Mycobacterium tuberculosis, and has positive value for the early diagnosis of silicotic tuberculosis and the reduction of leakage and misdiagnosis of silicosis recurrence. With the rise of silicosis, Bacillus L-type detection rate was significantly higher