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许多研究证实强力霉素除具有抗炎作用外,尚有神经保护作用,对脑卒中、多发性硬化、帕金森病及肌萎缩侧索硬化症等多种神经系统疾病均有保护作用。涉及的保护机制有抑制白细胞浸润、抑制基质金属蛋白酶活性、降低小胶质细胞活性和阻止细胞凋亡。具有一定的临床研究及应用价值。
Many studies have confirmed that doxycycline in addition to having anti-inflammatory effects, there are neuroprotective effects on stroke, multiple sclerosis, Parkinson’s disease and amyotrophic lateral sclerosis and other neurological diseases have a protective effect. The protective mechanisms involved are the inhibition of leukocyte infiltration, the inhibition of matrix metalloproteinase activity, the reduction of microglial activity and the prevention of apoptosis. Has a certain clinical research and application value.