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目的探讨新生儿中药中毒的临床特征及救治措施。方法本院2000年4月-2008年8月收治的新生儿中药中毒10例,其中罂粟壳中毒3例,六神丸中毒2例,神奇止咳冲剂、木通、黄连、大白及朱砂中毒各1例。入院后予9 g.L-1盐水或9 g.L-1盐水100 mL+西咪替丁0.2 g洗胃,10 g.L-1温盐水灌肠,葡醛内酯护肝,奥美拉唑或西咪替丁保护胃肠黏膜,呋塞米利尿,维持电解质酸碱平衡等对症处理,并根据不同情况予吸氧、升压药及抗心律失常药,罂粟壳中毒患儿予纳洛酮静脉注射。结果本组10例患儿经积极有效治疗,均痊愈出院,住院时间为1～14 d。结论新生儿中药中毒临床表现无特异性,病史采集困难,易误诊,应加强对新生儿中药中毒的毒理及防治研究。
Objective To investigate the clinical features and treatment of neonatal poisoning. Methods Ten cases of neonatal poisoning were treated in our hospital from April 2000 to August 2008, including 3 cases of poppy shell poisoning, 2 cases of Liushen Pill poisoning, 1 case of magical cough granules, Coptis, Coptis, Dabai and Cinnabar poisoning. After admission to 9 gL-1 saline or saline 9 gL-1 100 mL + cimetidine 0.2 g gastric lavage, 10 gL-1 warm saline enema, glucuronolase liver, omeprazole or cimetidine protection Gastrointestinal mucosa, furosemide diuretic, maintenance of electrolyte acid-base balance symptomatic treatment, and according to different circumstances to oxygen, vasopressors and anti-arrhythmic drugs, children with opium poppy poisoning to naloxone intravenously. Results The group of 10 cases of children treated by active and effective, were cured and discharged from hospital for 1 to 14 days. Conclusion neonatal poisoning clinical manifestations of non-specific, difficult to collect history, easy to misdiagnosis, should strengthen the toxicology and prevention and treatment of neonatal poisoning.