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目的观察适形放射治疗对肝转移瘤的治疗效果方法1997-09/1998-04我们采用立体定向适形放射治疗8例肝转移瘤(分别有1~5个转移灶),并进行了术后随访.肿瘤的临床靶体积(CTV)为0.6cm3~232cm3(平均36.4cm3),计划靶体积(PTV)最小照射量为每次照射3.96Gy~6.30Gy(平均5.08Gy),PTV最大照射量为每次照射5.63Gy~10.88Gy(平均6.84Gy),处方剂量(PD)为4.0Gy~6.5Gy(平均5.13Gy),分2~8次进行适形放射治疗.结果治疗过程中无1例死亡.患者一般状况的计分标准(KPS):术前20~90分(平均58.8分),术后30~100分(平均71.2分).实体瘤疗效标准:完全缓解(CR):2例:部分缓解(PR):3例;无变化(NC):2例;进展(PD):1例.在术后2mo~9mo随访期间,我们观察到87.5%的受照射肿瘤得到控制62.5%的肿瘤缩小或消失.结论立体定向适形放射治疗对肝转移瘤有良好的治疗效果.
Objective To observe the therapeutic effect of conformal radiation therapy on liver metastases. 1997-09/1998-04 We used stereotactic conformal radiotherapy to treat 8 cases of liver metastases (1 to 5 metastases, respectively) and performed postoperatively. Follow-up. The clinical target volume (CTV) of the tumor is 0.6cm3 to 232cm3 (average 36.4cm3), and the minimum target radiation volume (PTV) is 3.96Gy to 6.30Gy per irradiation (average 5.08Gy), and the maximum PTV The radiation dose was 5.63Gy to 10.88Gy (mean 6.84Gy) per irradiation, and the prescription dose (PD) was 4.0Gy to 6.5Gy (mean 5.13Gy), 2 to 8 times for conformal radiation therapy. Results There was no death in the course of treatment. The KPS of the patient’s general condition was 20 to 90 minutes (average 58.8 points) before surgery and 30 to 100 minutes (average 71.2 points). Solid tumor efficacy criteria: complete remission (CR): 2 cases: partial remission (PR): 3 cases; no change (NC): 2 cases; progress (PD): 1 case. During the follow-up period of 2 to 9 months, we Observed that 87.5% of the irradiated tumors were controlled 62.5% of the tumors shrink or disappear. Conclusion Stereotactic conformal radiotherapy has a good therapeutic effect on liver metastases.