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目的 探讨ＨＢＶ对幽门螺杆菌（ Ｈｐ）感染的影响。方法 利用Ｈｐ 全菌抗原检测ＨＢＶ、日本血吸虫单独或合并感染者血清Ｈｐ ＩｇＧ抗体。结果 ＨＢＶ与血吸虫合并感染时，血清ＨｐＩｇＧ抗体检出率（８５－７％ ）明显高于ＨＢＶ或血吸虫单独感染（阳性率分别为４５－５％ 和７２－９ ％），合并感染时血清ＨｐＩｇＧ抗体水平（０－８７±０－１０） 亦高于单独感染（０－７７±０－２０ ，０－７１ ±０－１７），差异有显著性意义。而ＨＢＶ阳性者与ＨＢＶ阴性者之间Ｈｐ 感染率和抗体水平相近。结论 ＨＢＶ 对Ｈｐ 感染具有促进作用，ＨＢＶ和血吸虫对Ｈｐ 感染具有协同相加作用。
Objective To investigate the effect of HBV on Helicobacter pylori (Hp) infection. Methods The Hp antigens were used to detect the serum Hp IgG antibodies of HBV and Schistosoma japonicum alone or in combination. Results The detection rate of HpIgG antibody in patients with HBV and schistosomiasis was significantly higher than that of HBV or Schistosoma japonicum alone (positive rates were 45-5% and 72-9%, respectively). Serum HpIgG antibody The level (0-87 ± 0-10) was also higher than the single infection (0-77 ± 0-20, 0-71 ± 0-17), the difference was significant. Hp infection rate and antibody level were similar between HBV-positive and HBV-negative. Conclusion HBV has a positive effect on Hp infection, and HBV and schistosomiasis have a synergistic effect on Hp infection.