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目的:探讨药物联合负压吸宫术对哺乳期妊娠流产的有效性及安全性。方法:选择200例哺乳期早期妊娠妇女随即分为药械联合终止早孕组(药械联合组)和负压吸宫术终止早孕组(负压吸宫组),比较两组间各临床指标。结果:药械联合组I级、Ⅱ级、Ⅲ级疼痛评价均较负压吸宫组明显降低(P<0.05)。两组在完全流产率和不全流产率上差异均无统计学意义(P>0.05)。药械联合组宫腔吸出组织量(2.48±0.77)mL明显高于(12.11±4.23)mL(P<0.05)。两组术后均无感染、闭经、器械性损伤和宫腔或宫颈粘连等并发症发生。结论:药械联合终止早孕有效、安全,疼痛及刮宫程度较轻。
Objective: To investigate the efficacy and safety of drugs combined with negative pressure suction aspiration for abortion during lactation. Methods: Two hundred and seventy pregnant women of early lactation period were randomly divided into three groups: termination of early pregnancy group (combination group) and vacuum termination of pregnancy group (group of negative pressure group). All clinical indexes were compared between the two groups. Results: The evaluation of grade I, grade II and grade III pain in the combination group was significantly lower than that in the group with negative pressure (P <0.05). There was no significant difference between the two groups in the rate of complete abortion and incomplete abortion (P> 0.05). The quantity of uterine aspiration tissue (2.48 ± 0.77) mL in the combination group was significantly higher than that in the group of (12.11 ± 4.23) mL (P <0.05). No postoperative infection, amenorrhea, mechanical injury and intrauterine or cervical adhesions and other complications occurred. Conclusion: The combination of medical device termination of early pregnancy effective, safe, pain and curettage degree less.