AIM:To evaluate the retinal vessel diameters in patients with migraine by optical coherence tomography(OCT).METHODS:In this cross-sectional study,124 eyes of 62 patients with a diagnosis of unilateral migraine during attack-free period and 42 age-and sex-matched control subjects were included. Migraine patients were divided into the ≤2 migraine attacks per month group and the ≥5 migraine attacks per month group. All subjects underwent complete ophthalmological and neurological examinations before measurements. Retinal vessel diameters and choroidal thickness were examined with the Spectralis OCT.RESULTS:The mean diameters of the arteries in the eyes on the headache side of control group,≥5 migraine attacks per month and ≤2 migraine attacks per month group at 480 μm from the optic disk(Raster 3)were 119.54±46.69,136.68±25.93 and 119.34±31.75 μm respectively with a steady decline to 105.57±32.15,118.18±31.87 and 108.05±38.77 μm at 1440 μm(Raster 7),the last measurement point,respectively. The retinal artery diameter measurements were significantly increased in ≥5 migraine attacks per month patients at four out of five measured points compared to control group(P<0.05). There were no statistical differences at any of the points of vein measurements. The choroidal thickness measurements were significantly decreased in ≥5 migraine attacks per month patients at all measured points compared to control group(P<0.05).CONCLUSION:The retinal artery diameter is found to increase significantly and the choroidal thickness is found to decrease in the eyes on the headache side in ≥5 migraine attacks per month patients compared to control group. AIM: To evaluate the retinal vessel diameters in patients with migraine by optical coherence tomography (OCT). METHODS: In this cross-sectional study, 124 eyes of 62 patients with a diagnosis of unilateral migraine during attack-free period and 42 age-and All subjects underwent complete complete ophthalmological and neurological examinations before measurements. Retinal vessel diameters and choroidal thickness were examined by: migraine attacks per month group and the ≥5 migraine attacks per month group. with the Spectralis OCT.RESULTS: The mean diameters of the arteries in the eyes on the headache side of control group, ≥5 migraine attacks per month and ≤2 migraine attacks per month group at 480 μm from the optic disk (Raster 3) were 119.54 ± 46.69, 136.68 ± 25.93 and 119.34 ± 31.75 μm respectively with a steady decline to 105.57 ± 32.15, 118.18 ± 31.87 and 108.05 ± 38.77 μm at 1440 μm (Raster 7), the last measurement point, respectively. The retinal artery measurements were significantly increased in ≥5 migraine attacks per month patients at four out of five measured points compared to control group (P <0.05). There were no statistical differences at any of the points of vein measurements . The choroidal thickness measurements were significantly decreased in ≥5 migraine attacks per month patients at all measured points compared to control group (P <0.05) .CONCLUSION: The retinal artery diameter is found to increase significantly and the choroidal thickness is found to decrease in the eyes on the headache side in ≥5 migraine attacks per month patients compared to control group.