在世界许多地区、布氏菌病都是一种明显的职业病。许多国家业已成功地根除了本地动物中的布氏菌病,从而减少了人类感染的机会。在美国,自40年来部分地由于最初为了减少牛群中布氏菌病的暴发流行而采取的监测和拔源措施,从而使人间布氏菌的流行也大为减少。病例数从1947年的高峰6321例减少到1972年的232例,更进一步减少到1989年的仅仅83例。然而,很清楚的是布氏菌感染并没有被完全诊断出来和报告上来。据估计,在美国每报告1个病例,大约就有26 In many parts of the world, brucellosis is a clear occupational disease. Many countries have succeeded in eradicating brucellosis in native animals, thereby reducing the chances of human infection. In the United States, the prevalence of B. intracellularis has also been drastically reduced, in part, over the past 40 years due in part to the monitoring and pull-out measures initially adopted to reduce the outbreak of brucellosis in herds. The number of cases dropped from 6,321 in 1947 to 232 in 1972 and further to only 83 in 1989. However, it is clear that the brucellosis infection has not been completely diagnosed and reported. It is estimated that there are about 26 cases reported in the United States for each case