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目的研究急性脑梗死患者C反应蛋白(CRP)水平及其变化与起病、病情及预后的关系。方法用OLYMPUSAO-TU400生化仪、德国德利曼公司试剂测定98例急性脑梗死患者入院时及治疗2周、1个月时的CRP水平,所有病例均行急诊CT检查及24h后复查,与正常对照组比较;并统计CRP与病情轻重及预后之间的关系。结果对照组CRP升高阳性率为6.0%;观察组为91.8%,急诊CT阳性率为58.2%。高CRP组神经功能缺失评分高,残疾率、死亡率均高。统计学处理均有显著性差异。结论CRP水平与急性脑梗死的发生、严重程度及预后呈正相关。
Objective To study the relationship between the level of C-reactive protein (CRP) and its changes in patients with acute cerebral infarction and its onset, disease and prognosis. Methods The CRP levels of 98 patients with acute cerebral infarction admitted to hospital and treated for 2 weeks and 1 month were measured with OLYMPUSAO-TU400 biochemical analyzer and German Deliman reagent. All patients underwent emergency CT examination and after 24 hours of follow-up, Control group; and statistical CRP with the severity and prognosis of the relationship. Results The positive rate of CRP in control group was 6.0%, in observation group was 91.8%, and the positive rate of CT in emergency group was 58.2%. High CRP neurological deficit score, disability rate, high mortality. Statistical analysis showed significant differences. Conclusion The level of CRP is positively correlated with the occurrence, severity and prognosis of acute cerebral infarction.