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1968年首次将淋巴瘤样丘疹病描述为一种具有恶性组织学表现、良性临床经过的少见皮肤病.自那时以来,经研究已证明有5～10%的病例可发展成症状明显的恶性肿瘤——通常是何杰金病,蕈样肉芽肿(MF)或一种大细胞非何杰金淋巴瘤.淋巴瘤样丘疹病与这些淋巴瘤的亚型之间的组织发生关系还了解甚少.但是.新近用单克隆抗体研究发现,淋巴瘤样丘疹病中的非典型细胞与这些恶性肿瘤
In 1968, lymphomatous papulosis was described for the first time as a rare skin disease with malignant histological manifestations and benign clinical course. Since then, studies have shown that 5-10% of cases can develop into manifestly malignant symptoms. Tumors - usually Hodgkin’s disease, mycosis fungoides (MF) or a large cell non-Hodgkin’s lymphoma. The histologic relationship between lymphomatoid papulosis and these lymphoma subtypes is also understood Few. However, recent studies using monoclonal antibodies have found that atypical cells in lymphomatoid papulosis and these malignancies