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患者,女,28a。曾有“荨麻疹”史。因输卵管粘连肌注糜蛋白酶(上海生物化学制药厂生产),隔日一次,5mg/次,肌注第十次后改为1次/d,在肌注第十四针后(1991年3月24日),当日即出现躯干部皮肤不规则红斑,高出皮肤,压之褪色伴搔痒。曾至某院就诊,因有油漆接触史而疑诊为“油漆过敏性皮炎”,给予口服扑尔敏片。翌日搔痒止,皮疹也消褪。于2d 后患者来本院继注糜蛋白酶针5mg,约5min 后即感头晕眼朦,胸闷气急,呕吐一次(非喷射性),随之汗出四肢厥冷,烦燥,血压测不清,脉搏不能触及,当即给予注射肾上腺素和地塞半松针并输液吸氧,约30min 后测血压为9/6kPa,脉搏为
Patient, female, 28a. Had “urticaria” history. Because of tubal adhesions in muscle chymase (Shanghai Biochemical Pharmaceutical Factory production), once every other day, 5mg / time, intramuscular injection after the tenth changed to 1 / d, intramuscular injection after the fourteenth needle (March 24, 1991 Day), the same day there is irregular erythema of the skin of the trunk, higher than the skin, pressure fade with itching. Has been to a hospital for treatment, due to paint contact history suspected of “paint allergic dermatitis”, given orally chlorpheniramine tablets. Itch the following day only, the rash also faded. 2d after the patient to the hospital following the injection of chymotrypsin needle 5mg, about 5min after feeling dizzy and dim, chest tightness and shortness of breath, vomiting (non-jet), followed by sweating limbs Jueleng, irritability, blood pressure test, Pulse can not touch, immediately give epinephrine injection and dexamethasone half needle and infusion oxygen, measuring blood pressure after about 30min 9 / 6kPa, pulse