慢性阻塞性肺疾病(COPD)在慢性呼吸系统疾病中较常见,而呼吸衰竭是其多见的一类并发症~[1]。目前治疗慢性阻塞性肺疾病合并严重呼吸衰竭的主要治疗方法为机械通气治疗~([2-3]),因其有效性、实用性特点等而日渐受到关注。本研究重在探讨利用序贯性机械通气方法治疗非COPD所致严重呼吸衰竭的疗效及临床护理,为进一步治疗该病提供科学依据,现报道如下。1资料与方法1.1研究对象NIV组:收集2014年1月至2016年 Chronic obstructive pulmonary disease (COPD) is more common in chronic respiratory diseases, and respiratory failure is a more common type of complication [1]. At present, the main treatment for chronic obstructive pulmonary disease (COPD) complicated with severe respiratory failure is mechanical ventilation therapy ([2-3]), which is attracting more and more attention due to its effectiveness and practicability. This study focuses on the use of sequential mechanical ventilation for non-COPD-induced severe respiratory failure, efficacy and clinical nursing, to provide a scientific basis for further treatment of the disease, are reported below. 1 Materials and Methods 1.1 Study Group NIV: collected from January 2014 to 2016