Review of General Algorithmic Features for Genome Assemblers for Next Generation Sequencers

来源 :黑龙江科技信息 | 被引量 : 0次 | 上传用户:sunrainnet
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
In the realm of bioinformatics and computational biology,the most rudimentary data upon which all the analysis is built is the sequence data of genes,proteins and RNA.The sequence data of the entire genome is the solution to the genome assembly problem.The scope of this contribution is to provide an overview on the art of problem-solving applied within the domain of genome assembly in the nextgeneration sequencing (NGS) platforms.This article discusses the major genome assemblers that were proposed in the literature during the past decade by outlining their basic working principles.It is intended to act as a qualitative,not a quantitative,tutorial to all working on genome assemblers pertaining to the next generation of sequencers.We discuss the theoretical aspects of various genome assemblers,identifying their working schemes.We also discuss briefly the direction in which the area is headed towards along with discussing core issues on software simplicity.
其他文献
罗牧是明末清初“江西派”开派山水画家,也是中国古代山水画杰出而有成就的画家之一,在中国美术史上有一定的地位和影响。虽历经三百多年,罗牧的绘画艺术,仍对中国山水画产生影响
期刊
本文从生活方式和身体媒介艺术创作的关系展开讨论,讨论生活方式对身心的影响以及身体媒介艺术本身的内涵和作品案例。除了理论的梳理和阐释,亦结合本人的实践和教学里的观察和
目前我们对城市户外公共设施设计的研究虽然从多方展开,已经考虑包括形式美感、使用功能等多方面的因素,但还缺少对其所在区域文化内涵的关注。在设计思维不断革新的今天,城
全景写意花鸟画置景形式之所以能在花鸟画发展史上千百年来不断的对后世产生重大影响,一个重要的因素就是在经营位置和题材选择上不断的变化且丰富多样。随着时代的转变,在中
期刊