Selective inhibition of Hepatocarcinoma cells by apatite nanoparticles

来源 :Chinese Journal of Biomedical Engineering(English Edition) | 被引量 : 0次 | 上传用户:williamchu2008
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The effects of HAP nanoparticles on growth of primary normal animal liver cells and on growth of hepatocarcinoma cell line Bel 7402 in vitro were studied respectively and were compared with each other.The results showed that HAP nanoparticles in certain concentration inhibited growth of cancer cells significantly while did not inhibite normal cells in the same concentration.The inhibition ratio was as high as very high dosage of adriamycin.It was concluded that HAP nanoparticles can selectively inhibited cancer cells. The effects of HAP nanoparticles on growth of primary normal animal liver cells and on growth of hepatocarcinoma cell line Bel 7402 in vitro were studied respectively and were compared with each other. The results showed that HAP nanoparticles in certain concentration inhibited growth of cancer cells significantly while did not inhibite normal cells in the same concentration. The inhibition ratio was as high as very high dosage of adriamycin. It was concluded that HAP nanoparticles can selectively inhibited cancer cells.
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