肝硬化是各种慢性肝病的晚期阶段,其病理学定义为弥漫性肝脏纤维化伴有异常结节形成。从临床角度看,肝硬化主要表现为肝细胞功能衰竭(血清白蛋白降低、胆红素升高、凝血酶原时间延长等)和门静脉高压症(食管胃底静脉曲张及其破裂出血、腹水、自发性细菌性腹膜炎及肝肾综合征、肝性脑病等)。近年有关肝硬化的临床研究尚无突破性进展,目前尚缺乏对肝硬化的特效治疗方法。因此,临床医师更应树立以人为本的观点,为患者制定系统、规范的诊断治疗方案及随访计划。 Cirrhosis is a late stage of various chronic liver diseases, the pathology of which is defined as diffuse hepatic fibrosis with abnormal nodule formation. From a clinical point of view, cirrhosis of the liver is mainly manifested as liver failure (serum albumin, elevated bilirubin, prothrombin time, etc.) and portal hypertension (esophageal varices and bleeding rupture, ascites, Spontaneous bacterial peritonitis and hepatorenal syndrome, hepatic encephalopathy, etc.). In recent years, clinical research on cirrhosis no breakthrough, there is still no lack of treatment for liver cirrhosis. Therefore, clinicians should establish a people-oriented point of view, for patients to develop systematic, standardized diagnosis and treatment programs and follow-up plan.