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同型半胱氨酸是蛋氨酸脱甲基代谢中产生的一种含硫氨基酸 ,它对内皮细胞有毒性作用以及凝血和促凝血作用 ;妊高征患者存在高同型半胱氨酸血症 ,并与其内皮细胞损伤有关 ;妊高征高同型半胱氨酸血症可能与叶酸、维生素B12 缺乏及遗传因素有关
Homocysteine is a sulfur-containing amino acid produced by demethylation of methionine and has toxic effects on endothelial cells as well as coagulation and procoagulant effects. Hyperhomocysteinemia is present in patients with PIH and is associated with Endothelial cell injury; PIH hyperhomocysteinemia may be related to folic acid, vitamin B12 deficiency and genetic factors