子宫内膜癌已成为妇科常见恶性肿瘤之一,为性激素依赖性肿瘤,与遗传因素密切相关。最近,越来越多的研究从基因多态的角度探讨此病的患病风险,研究内容涉及性激素受体基因多态及与之相关的一些基因多态。综述了近五年来国外有关此方面的一些研究进展,希望从遗传学的角度探讨该病的患病风险,为临床治疗提供理论基础。 Endometrial cancer has become a common gynecological malignant tumors, sex hormone-dependent tumors, and genetic factors are closely related. Recently, more and more researches have investigated the risk of this disease from the perspective of genetic polymorphism. The research involves the gene polymorphisms of sex hormone receptor and related gene polymorphisms. This review summarizes some research progress in this field abroad in the past five years and hopes to explore the risk of the disease from the perspective of genetics and provide a theoretical basis for clinical treatment.