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为探讨甲状腺上皮样血管内皮瘤的病理形态特征、免疫表型和鉴别诊断,对2例甲状腺上皮样血管内皮瘤进行临床资料分析、随访,并观察其病理形态及免疫组织化学染色分析。2例甲状腺上皮样血管内皮瘤均位于甲状腺下极,实性,切面暗红色,镜下由增生的血管内皮细胞构成,具有上皮样细胞形态,胞浆较丰富,嗜酸性,多呈空泡状,细胞间可见血管腔,免疫组化:CD34(+)、Vim(+)、细胞角蛋白(cytokeratin,CK)(-)、甲状腺球蛋白(thyroid globulin,TG)(-)。上皮样血管内皮瘤是一种罕见的甲状腺肿瘤,其生物学行为属于低度恶性。
To investigate the pathological features, immunophenotypes and differential diagnosis of thyroid epithelioid hemangioendothelioma, the clinical data of 2 cases of thyroid epithelioid hemangioendothelioma were analyzed and followed up. The pathological changes and immunohistochemical staining were also observed. 2 cases of thyroid epithelioid hemangioendothelioma are located in the thyroid gland, solid, dark red section, microscope by the proliferation of vascular endothelial cells, with epithelial cell morphology, cytoplasm more abundant, eosinophilic, mostly vacuolar The intraluminal cavities were observed. Immunohistochemistry showed that there were CD34 (+), Vim (+), cytokeratin (CK) and thyroid globulin (-). Epithelioid hemangioendothelioma is a rare thyroid tumor whose biological behavior is of low malignancy.