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目的探讨高压交变电场疗法对更年期综合征治疗的有效性。方法将更年期综合征患者128例分为治疗组和对照组,每组64例,治疗组接受HES-A30型30 kV高压交变电场治疗,对照组接受同一条件的“无电治疗”。全部病例均于治疗前、后行临床及实验室的相关检查,并于治疗前、中、后分别做随诊记录、目测类比评分(VAS)、Kupperman更年期症状评分(K评分)及不良反应记录。全部数据经SPSS 12．0软件统计分析。结果治疗组疗效显著优于对照组(P<0．001);高压交变电场治疗对雌二醇(E2)、促卵泡激素(FSH)水平的影响不明显(P>0．05),对血压和心电图、乳腺和妇科体征、血像、肝和肾功能无明显影响(P>0．05);无与治疗相关的不良反应。结论 HES-A30高压交变电场对更年期综合征的治疗效果良好、安全。
Objective To investigate the effectiveness of high voltage alternating electric field therapy in the treatment of menopausal syndrome. Methods 128 cases of climacteric syndrome were divided into treatment group and control group, 64 cases in each group. The treatment group received HES-A30 30 kV high-voltage alternating electric field and the control group received the same condition of “no-power treatment.” All cases were examined before and after treatment in clinical and laboratory, and were followed up before, during and after treatment, visual analogue scale (VAS), Kupperman menopause symptom score (K score) and adverse reaction records . All data by SPSS 12.0 software statistical analysis. Results The therapeutic effect of the treatment group was significantly better than that of the control group (P <0.001). The effect of high voltage alternating electric field on estradiol (E2) and follicle stimulating hormone (FSH) was not significant (P> 0.05) Blood pressure and electrocardiogram, breast and gynecological signs, blood images, liver and kidney function had no significant effect (P> 0.05); no adverse reactions associated with treatment. Conclusion HES-A30 high-voltage alternating electric field treatment of climacteric syndrome effect is good and safe.