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目的了解临床分离的酵母样真菌感染现状及分布特点,为减少真菌感染和控制医院感染提供实验依据。方法采用回顾性调查方法,对本院2013年1月-12月临床各科送检标本3 421份用沙保罗氏培养基和念珠菌显色培养基分离真菌,用ATB ID32C酵母菌鉴定板条鉴定真菌。结果临床标本共3 421份,培养阳性138份,阳性率为4.03%,符合医院感染共27例,其中局部感染25例,全身感染2例。全部患者均有基础性疾病,且均使用过多种广谱抗生素。结论医院酵母样真菌感染主要多发生于年老体弱、免疫功能低下、导管留置和长期使用广谱抗生素的患者,已成为医院感染的主要因素之一。
Objective To understand the status and distribution of clinically isolated yeast-like fungal infections and provide experimental evidence for reducing fungal infection and controlling nosocomial infections. Methods A retrospective investigation method was used to separate the fungi from 3 421 samples of clinical specimens from January to December in 2013 in Shabulun and Candida chromogenic medium and the identification of laths by ATB ID32C yeast Identification of fungi. Results A total of 3 421 clinical specimens were collected, and 138 were positive for culture. The positive rate was 4.03%. There were 27 cases with nosocomial infection, including 25 cases of local infection and 2 cases of systemic infection. All patients had underlying disease and had used various broad-spectrum antibiotics. Conclusions Hospital-based yeast-like fungal infections mainly occur in the elderly and infirm, immunocompromised, catheterized and long-term use of broad-spectrum antibiotics has become one of the main factors of nosocomial infection.