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通过对云南省云龙县恙虫病立克次体分离株对实验动物的致病性研究表明，各分离株对小白鼠和豚鼠均有较强的致病性，对家兔亦有一定的致病性，而恒河猴则不敏感；经毒力测定，７个分离株中，有５株ＬＤ５０≥８．５，为强毒株。该县恙虫病立克次体分离株抗原型以Ｇｉｌｉａｍ型为主，其次为Ｋａｒｐ型，不同的抗原型株间有很强的交互保护力。
The pathogenicity of the Rickettsia tsutsugamushi isolate of Yunji County in Yunnan Province to experimental animals showed that all the isolates had strong pathogenicity to mice and guinea pigs and also had certain pathogenicity to rabbits While Rhesus macaques was insensitive. According to the virulence test, among the 7 isolates, 5 strains were LD50≥8.5, which was a virulent strain. The strain of Rickettsia tsutsugamushi isolated in this county is mainly Giliam type, followed by Karp type, with strong mutual protection between different antigenic strains.