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２０多年来，采用“两系法”配制陆地棉品种间杂交种，先后选育出“洞Ａ”、“７５１Ａ”、“４７３Ａ”、“ＭＡ”核不育系，与此同时，研究建立了与核不育相适应的良繁体系及种子生产体系。先后筛选培育出了川杂１、２、３、４、６号，内杂１号、杂交早熟系列杂交种，平均增产皮棉１７６．５５ｋｇ／ｈｍ２，累计推广面积５０万公顷。近年来，又从“洞Ａ”系中，培育成功一种核不育完全保持系即ＭＢ系，利用ＭＢ系同核不育系（ｍｃ１ｍｃ１）杂交生产一种新的不育系即ＭＡ系（ｍｃ１ｍｃ１），其后代不育株率达１００％，不育度达９５％～１００％。采用“二级法”实现了核不育“三系”配套。标志着利用核不育系配制杂交种应用于生产的又一次重大突破，将有力地推动四川杂交棉研究和应用的发展。
For more than 20 years, the two-line method has been used to prepare cross-species hybrids of upland cotton. The “A”, “751A”, “473A” and “MA” sterile lines have been bred at the same time. Good reproductive system and seed production system adapted to nuclear infertility. Successively screened to breed hybrid No. 1, 2, 3, 4, 6, No. 1 miscellaneous hybrids, hybrid early hybrids series, with an average increase of lint 176.55kg / hm2, the cumulative promotion of an area of 500,000 hectares. In recent years, from the “Cave A” line, we successfully cultivate a full line of male sterility, MB line, and use the MB line with the male sterile line (mc1mc1) to produce a new CMS line mc1mc1), the offspring rate of infertile plants up to 100%, sterility of 95% to 100%. Adopting the “secondary law” to achieve “three lines” of nuclear infertility. Marked another major breakthrough in the use of nuclear sterile lines formulated hybrids used in production, will effectively promote the Sichuan hybrid cotton research and application development.