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目的:探讨奥曲肽与乌司他丁联合治疗急性胰腺炎患者的临床效果。方法:选取我院收治的急性胰腺炎患者136例作为研究对象,运用随机分组法分为观察组和对照组,每组各68例,观察组患者采用奥曲肽与乌司他丁联合治疗的方法,对照组单纯采用奥曲奥曲肽进行治疗,对比两组患者临床治疗有效率和不良反应的发生率;临床症状消失时间,血清淀粉酶、尿淀粉酶水平恢复正常时间和住院时间。结果:观察组患者临床治疗有效率明显高于对照组患者的临床治疗有效率;观察组患者的不良反应发生率明显少于对照组患者的不良反应发生率;观察组患者的临床症状消失时间,血清淀粉酶、尿淀粉酶水平恢复正常时间和住院时间相对于对照组均较少,P<0.05,具有统计学意义。结论:选用奥曲肽联合乌司他丁的治疗方法效果显著,安全性高,副作用发生率较少,值得在临床推广和使用。
Objective: To investigate the clinical effect of octreotide combined with ulinastatin in the treatment of acute pancreatitis. Methods: A total of 136 patients with acute pancreatitis admitted to our hospital were enrolled in this study. They were randomly divided into observation group and control group, with 68 cases in each group. The patients in observation group were treated with octreotide and ulinastatin, The control group was treated with octreotide alone. The incidences of clinical efficacy and adverse reactions were compared between the two groups. The disappearance of clinical symptoms, serum amylase, urinary amylase levels were restored to normal and hospitalized. Results: The effective rate of clinical treatment in the observation group was significantly higher than that in the control group. The incidence of adverse reactions in the observation group was significantly less than that in the control group. The disappearance of clinical symptoms, Serum amylase, urinary amylase levels returned to normal time and hospitalization time relative to the control group were less, P <0.05, with statistical significance. Conclusion: The treatment with octreotide combined with ulinastatin is effective, safe and has fewer side effects. It is worthy of clinical promotion and use.