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猪苓多糖是由多孔菌科植物猪苓Pdyporus umbe atus[Pers.]Fr提取而成,目前认为该药物对肿瘤的治疗有一定的疗效。因此,已日益被人们所重视,为了进一步探讨该药物的抗诱变作用,我们利用该药物对环磷酰胺(Cydophosphomidum,Cy)诱发小鼠体内骨髓红细胞的微核试验进行初步研究,现将结果报告如下。材料 1.药品猪苓多糖:由连云港东风制药厂提供,批号911102。环磷酰胺:由上海第十二制药厂生
Polyporus umbellatus polysaccharides are extracted from Polyporaceae Pdyporus umbe atus [Pers.] Fr. It is currently considered that the drug has a certain effect on the treatment of tumors. Therefore, it has been increasingly valued by people. In order to further explore the antimutagenicity of the drug, we used the drug to conduct preliminary studies on the micronucleus test of bone marrow erythrocytes induced by Cydophosphomidum (Cy) in mice. The report is as follows. Materials 1. Drugs Polyporus polysaccharides: provided by Lianyungang Dongfeng Pharmaceutical Factory, lot number 911102. Cyclophosphamide: Produced by Shanghai Twelfth Pharmaceutical Factory