论文部分内容阅读
作者研究了氯化琥珀胆碱注射液在各种条件下的稳定性。按处方组成加入氯化钠、对羟基苯甲酸甲酯和盐酸适量,配制浓度为10 mg/ml的氯化琥珀胆碱注射液。考察溶液的pH(3.0和4.2)、消毒灭菌(100℃ 30分钟和121℃20分钟)及贮存温度(4～6℃、20～26℃、35℃、70℃)和连续光照12个月对稳定性的影响,同时还考察了4℃存放2、17、23个月后注射液的稳定性。本实验采用TLC法和HPLC法测定含量。
The authors studied the stability of succinylcholine chloride injection under various conditions. According to the prescription, sodium chloride, methyl paraben and hydrochloric acid were added to prepare the succinylcholine chloride injection at a concentration of 10 mg / ml. The solution pH (3.0 and 4.2), disinfection and sterilization (100 ℃ for 30 minutes and 121 ℃ for 20 minutes) and storage temperature (4 ~ 6 ℃, 20 ~ 26 ℃, 35 ℃, 70 ℃) On the stability, but also investigated the stability of the injection after 2, 17, 23 months storage at 4 ℃. The experiment using TLC method and HPLC determination of content.