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目的 :研究胃癌单克隆抗体的表达及临床意义。方法 :用本室制备的对胃癌有较强特异性的McAbGMG1:1D1- 2对 15 1例内窥镜活检组织压印片进行免疫组织化学检查。结果 :用本法检查组织印片中的癌细胞以及具有癌细胞相关抗原的癌前病变组织 ,特异性强 ,反应灵敏 ,结果可靠。结论 :如果与内窥镜和常规病理学检查联合应用 ,会提高早期癌的检出率 ,本文还就抗人胃癌McAb与CP的相关性进行了初步探讨。
Objective: To study the expression and clinical significance of monoclonal antibodies against gastric cancer. METHODS: Immunohistochemical examination of 151 cases of endoscopic biopsy specimens was performed using McAbGMG1:1D1-2, which has strong specificity for gastric cancer. RESULTS: This method was used to examine the cancer cells in tissue prints and precancerous lesions with cancer-associated antigens. The specificity was strong, the reaction was sensitive, and the results were reliable. Conclusion : If combined with endoscopy and routine pathological examination, will increase the detection rate of early cancer, this article also on the anti-human gastric cancer McAb and CP correlation.