药物性肝损害(drug-induced hepatitis)是抗结核药最常见的毒副作用之一,其发生率居首位,对人体影响最大,也是结核病人停止化疗的最常见原因之一〔1〕。李群安的研究表明,抗结核期间92%(48/52)的肺结核病人的肝代谢功能下降,不同程度的药物性肝损害肯定存在〔2〕。本文就抗结核 Drug-induced hepatitis is one of the most common side effects of antituberculosis drugs. Its incidence rate ranks the first place and has the greatest impact on the human body. It is also one of the most common causes of stopping chemotherapy in tuberculosis patients [1]. Li Qunan studies have shown that 92% (48/52) of tuberculosis patients during anti-TB decreased liver metabolic function, varying degrees of drug-induced liver damage certainly exist [2]. This article on anti-TB