肝内胆汁淤积(Intrahepatic Cholestasis)系指由不同原因引起的肝内胆汁排泄障碍。其特点为胆汁的各种成分于血中停滞,特别是胆盐(bile salts)的停滞,同时合并结合胆红素的潴留。肝内胆汁淤积是肝病的常见病理变化,它的原因很多,但其临床表现均以黄疸为主,与肝外梗阻常不易鉴别,且有些病例,治疗困难。为此,将有关肝内胆汁淤积的病因、临床类型、诊断、治疗等方面的问题,综述如下。 Intrahepatic Cholestasis refers to disorders of intrahepatic bile excretion caused by different causes. It is characterized by various components of the bile in the blood stagnation, especially the bile salts (bile salts) stagnation, combined with the combination of bilirubin retention. Intrahepatic cholestasis is a common pathological change of liver disease, its many reasons, but its clinical manifestations are mainly jaundice, and often difficult to identify extrahepatic obstruction, and in some cases, the treatment is difficult. To this end, the etiology, clinical type, diagnosis, treatment and other aspects of intrahepatic cholestasis are summarized as follows.