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依据肝硬变形成的病因,探讨肝硬变病理改变能否逆转和肝硬变病因治疗。任选经临床和病理检查确诊的早期和代偿期肝硬变病例70例,肌注具有明确抑制HBV复制和消退肝内炎症药物八八乙肝泰,同时观察临床征象和肝功能变化,重复肝活检。结果,治疗5个月后729%可获自觉征象消退和肝功能正常,114%基本正常,143%进步;肝活检复查早期肝硬变病理特征619%消退,333%进步;代偿期肝硬变假小叶714%消退,286%进步。结论:肝硬变的治疗原则仍在于有效控制消退肝内慢性炎症,确切有效的消退肝内炎症药物可以有效的治疗肝硬变,逆转其病理变化,因而肝硬变是可以防治的。
According to the etiology of cirrhosis, to investigate whether the pathological changes of cirrhosis can be reversed and the cause of cirrhosis treatment. Optional clinical and pathological examination confirmed 70 cases of early and decompensated cirrhosis, intramuscular injection of a clear inhibition of HBV replication and the eradication of intrahepatic inflammatory drugs Baabaguanteng, while observing the clinical signs and changes in liver function, repeated liver Biopsy. Results, 729% after 5 months of treatment can be felt signs of regression and normal liver function, 114% of the normal, 143% progress; liver biopsy review of pathological features of early cirrhosis 619% regression, 333% progress; compensated cirrhosis False leaflets 714% subsided, 286% progress. Conclusion: The treatment of cirrhosis is still the principle of effective control of chronic liver inflammation to eliminate the extinction of liver inflammation can effectively effectively treat cirrhosis and reverse the pathological changes, so cirrhosis can be prevented.