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目的比较西咪替丁、更昔洛韦及利巴韦林治疗小儿水痘的疗效。方法将60例水痘患儿随机分3组,在其他治疗相同的基础上分别应用西咪替丁、更昔洛韦及利巴韦林组治疗,疗程5天观察疗效。结果西咪替丁组有效率达85%,更昔洛韦组有效率达95%,利巴韦林组有效率达55%;西咪替丁与更昔洛韦组症状、体征好转时间相比无显著性差异,与利巴韦林组相比均有明显优势。结论西咪替丁和更昔洛韦治疗小儿水痘疗效显著。
Objective To compare the efficacy of cimetidine, ganciclovir and ribavirin in the treatment of chickenpox in children. Methods Sixty children with chickenpox were randomly divided into three groups, and treated with cimetidine, ganciclovir and ribavirin respectively on the basis of the same treatment. The curative effect was observed after 5 days of treatment. Results The effective rate was 85% in the cimetidine group, 95% in the ganciclovir group, and 55% in the ribavirin group. The symptoms and signs of cimetidine and ganciclovir were improved No significant difference compared with ribavirin group have obvious advantages. Conclusion The efficacy of cimetidine and ganciclovir for the treatment of chickenpox in children is significant.