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在不育的病因中,排卵功能紊乱约占15～20%。目前虽已有多种监测排卵的指标,但尚有不足之处。腹腔液是输卵管已排出的卵子的生理环境。在卵泡破裂后,卵泡液也成为腹腔液的一部分。基于用口服避孕药妇女、绝经后妇女以及正常男性仅有少量腹腔液,提示腹腔液的产生部分地取决于卵巢的外分泌活动。用腹腔镜可观察排卵点,但此较主观且从阴性结果无法下结论。显然,从抽吸出的腹腔液中检测存在于卵泡液中的某种化学指标可以作为一种更为客观的判断卵泡破裂和卵子排出的手段。曾有报导用雌二醇及孕酮的变化作为指标,但二者均为小分子且易于通过细胞膜,因此也可从完整的卵泡进入腹腔液。因此,观察卵泡液中某种较大的分
In the etiology of infertility, ovulation disorders account for about 15 to 20%. Although there are many indicators of ovulation monitoring, there are still some shortcomings. Peritoneal fluid is ovulated oviduct physiological environment. Follicular fluid also forms part of the peritoneal fluid after the rupture of the follicle. Based on the fact that women with oral contraceptives, postmenopausal women, and normal men have only a small amount of peritoneal fluid, it is suggested that the production of peritoneal fluid depends in part on the exocrine activity of the ovary. Ovulation can be observed with laparoscopy, but this subjective and negative results can not be concluded. Obviously, detecting a chemical index present in follicular fluid from aspirated peritoneal fluid can be used as a more objective measure of follicular rupture and egg release. It has been reported that changes in estradiol and progesterone are used as indices, but both are small molecules and easily pass through the cell membrane and thus also enter the peritoneal fluid from intact follicles. Therefore, observe a larger fraction of follicular fluid