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目的:探究鸦胆子油乳联合放疗治疗脑质瘤的临床效果。方法:选取我院2008年1月-2011年1月间脑质瘤患者42例,治疗组22例,采用鸦胆子油乳联合放疗治疗;对照组20例,采用司莫司汀联合放疗治疗,分别观察两组病例完全缓解、部分缓解、稳定以及恶化病例数,以完全缓解与部分缓解合计有效率,同时观察两组的毒副作用,计算不良反应率,比较两组治疗效果与毒副反应。结果:治疗组有效率72.2%,对照组有效率70.0%,两者差异无统计学意义(P>0.05),治疗组不良反应率18.1%,对照组40%,两者差异有统计学意义(P<0.05)。结论:鸦胆子油乳联合放疗治疗脑质瘤与司莫司汀联合放疗治疗两者临床疗效相似,且鸦胆子油乳毒副作用较小,适合在临床治疗脑质瘤上推广应用。
Objective: To investigate the clinical effect of Brucea javanica oil combined with radiotherapy in the treatment of brain tumor. Methods: Forty-two patients with brain tumor from January 2008 to January 2011 were selected. Twenty-two patients in the treatment group received Brucea javanica oil combined with radiotherapy. In the control group, 20 patients were treated with semustine plus radiotherapy, The complete remission, partial remission, stable and exacerbation of the two groups were observed. The total effective rate of complete remission and partial remission were observed. The side effects of the two groups were observed, and the adverse reaction rate was calculated. The treatment effect and side effects were compared between the two groups. Results: The effective rate was 72.2% in the treatment group and 70.0% in the control group, with no significant difference between the two groups (P> 0.05). Adverse reaction rate was 18.1% in the treatment group and 40% in the control group, with significant difference P <0.05). CONCLUSION: Brucea javanica oil combined with radiotherapy for the treatment of both brain tumor and cemustine combined with radiotherapy have similar clinical curative effect. Brucea javanica oil and milk have fewer side effects and are suitable for clinical application in treating brain tumor.