目的：探讨急性心肌梗塞（ＡＭＩ）溶栓治疗后冠脉再通对患者近期及远期预后的影响。方法：将７８例 ＡＭＩ溶栓治疗患者分为再通组４７例，未通组３１例，比较两组住院期间和随诊期间的病死率及并发症发生率。结果：住院期间再通组心力衰竭、心源性休克、恶性室性心律失常及梗塞扩展的发生率及病死率均低于未通组。随诊期间再通组病死率、心力衰竭发生率及室壁瘤检出率均低于未通组。结论：及时的再灌注可明显地改善ＡＭＩ患者住院和随诊期间的心功能，减少恶性室性心律失常和室壁瘤的发生率，降低病死率，提示冠脉再通可改善ＡＭＩ患者近期及远期预后。 Objective: To investigate the effect of coronary recanalization on the short-term and long-term prognosis of acute myocardial infarction (AMI) thrombolytic therapy. Methods: A total of 78 AMI thrombolytic patients were divided into reperfusion group (n = 47) and failed group (n = 31). The mortality and complication rate between the two groups during hospitalization and follow-up were compared. Results: The incidence and mortality of heart failure, cardiogenic shock, malignant ventricular arrhythmia and infarct expansion in the recanalization group during hospitalization were lower than those in the non-recanalization group. Follow-up recanalization group mortality, heart failure incidence and detection rate of aneurysms were lower than the failed group. Conclusion: Timely reperfusion can significantly improve the cardiac function during hospitalization and follow-up of patients with AMI, reduce the incidence of malignant ventricular arrhythmias and ventricular aneurysms and reduce the mortality, suggesting that recanalization of coronary artery can improve the short-term and long-term AMI patients Prognosis.