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随着医疗新技术的迅速发展,造血干细胞移植在临床上的用途越来越广泛。移植后供者源细胞几乎存在于受者所有组织,必然对个人识别和亲权鉴定产生重要影响,应引起法医工作者的重视,避免因此而产生错误的司法鉴定结论。本文就近年来allo-HSCT受者不同组织DNA嵌合状态的研究进展及其对法医物证鉴定的影响作一综述,希望能对相关研究和实践提供参考。
With the rapid development of new medical technologies, hematopoietic stem cell transplantation has become more and more widely used in clinical practice. After transplantation, the donor cells exist in almost all tissues of the recipient, which will inevitably have an important impact on the identification and paternity testing. Therefore, forensic workers should pay attention to avoid the mistaken forensic conclusions. This review summarizes the research progress of DNA chimerism in different tissues of allo-HSCT recipients in recent years and its impact on the identification of forensic medical evidence. It is hoped that it can provide references for related research and practice.