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许多间歇急性型血卟啉症女病人的发作与月经有关。作者用口服避孕药预防此症的发作,报道如下: 病例和方法自1960年至1974年4月,作者观察了14例间歇急性型血卟啉症女病人的病程。年龄30～51岁,平均38.4岁。除死亡2例(39岁)外,12例中7例在一次急性发作后即分别给予口服避孕药Ovulen(炔雌醇0.1毫克或炔雌甲醚0.1毫克+乙二醇二乙酯1毫克,Ovanon(炔雌醇0.075或0.08毫克+Lynestrenol 2.5毫克),Eugynon(炔雌醇0.05毫克+DL-18-甲基炔诺酮0.5毫克)或Anovlar(炔雌酵0.05毫克+醋炔诺酮4毫克)。服药时间为1～7.5年,平均为5年。其中5例的急性发作在时间上与月经有关。1例做了两侧卵巢摘除术,另1例用X线照射两侧卵巢使之丧失功能。余5例作为对照组。观察期间作了血压和肝、肾功能等检查。
Many episodes of acute episodes of hematoporphyrin female patients are associated with menstruation. The authors use oral contraceptives to prevent the onset of the disease, reported as follows: Cases and methods From 1960 to April 1974, the authors observed the duration of 14 patients with intermittent acute blood porphyria disease. Aged 30 to 51 years old, with an average of 38.4 years old. In addition to 2 deaths (39 years), 7 of 12 patients were given oral contraceptive Ovulen (ethinyl estradiol 0.1 mg or ethynylestradiol 0.1 mg + ethylene glycol diethyl ester 1 mg, respectively) after an acute attack, Ovanon (Ethinyl estradiol 0.075 or 0.08 mg + Lynestrenol 2.5 mg), Eugynon (Ethinyl estradiol 0.05 mg + DL-18-norgestrel 0.5 mg) or Anovlar (Ethinyl estradiol 0.05 mg + Norethindrone acetate 4 mg ) .During the medication for 1 to 7. 5 years, an average of 5 years .Among them, 5 cases of acute attack in time and menstrual related.One case of ovariectomy on both sides, the other with X-ray on both sides of the ovary Loss of function.The remaining five cases as a control group during the observation made blood pressure and liver and kidney function tests.