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乳腺癌(BC)是发生在35~75岁女性中较为普遍的恶性肿瘤~([1]),也是全球癌症相关死亡的主要原因之一。在过去的几年中,学术界对乳腺癌相关的分子标记物进行了广泛的研究,并发现了BC的异质性特点,也使我们对乳腺癌治疗过程中肿瘤的生物学行为更容易理解和预测。目前学术界普遍认为,根据基因表达谱,按照病理类型的不同,将BC分为不同的类型,如侵袭性BC和非侵袭性BC~([2-5]),通过这种新的分类为BC的生物学特点提供新的见解,且可能在不久的将来,应用于BC的临床治疗,为多种疾病的传统病理学诊断提供巨大的支持(包括形态学、免
Breast cancer (BC) is a more common malignancy in women aged 35-75 years (1) and is one of the leading causes of cancer-related death worldwide. In the past few years, extensive research into molecular markers associated with breast cancer has been carried out in academia and the heterogeneity of BC has been uncovered, allowing us to better understand the biological behavior of tumors in the treatment of breast cancer And forecast. Currently the academic community generally believes that according to the gene expression profiling, BC is divided into different types, such as invasive BC and non-invasive BC ~ ([2-5]), according to the different pathological types, by this new classification The biological characteristics of BC provide new insight and may be applied to the clinical treatment of BC in the near future, providing great support for the traditional pathological diagnosis of many diseases (including morphology, immunity