临床调查显示,入住NICU的新生儿,尤其是早产儿暴露于频繁的致痛性操作,这些未予任何干预的疼痛刺激对儿童远期健康的影响已引起儿科医师越来越多的关注。基于新生儿早期经历大量致痛性操作的现状和生命早期脑发育的可塑性,本文将综述新生儿疼痛对儿童行为发育的影响和机制两方面的研究现状,为新生儿疼痛的早期预防和干预提供科学依据。 Clinical studies have shown that neonatal NICU admission, especially premature infants exposed to frequent painful operation, these no pain intervention to interfere with the long-term health of children has drawn increasing concern of pediatricians. Based on the status of new episodes of painful maneuvers and early childhood brain developmental plasticity, this article reviews the current research on the effects and mechanisms of neonatal pain on children’s behavioral development, and provides early prevention and intervention for neonatal pain Scientific basis.