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1文献来源Fareed KR,Al-Attar A,Soomro IN,et al.Tumour regression and ERCC1 nuclear protein expression predict clinical outcome in patients with gastro-oesophageal cancer treated with neoadjuvant chemotherapy[J].Br J Cancer,2010,102(11):1600-1607.2证据水平1a。3背景胃食管肿瘤是一种常见的、高致命性疾病,以铂类为基础的新辅助化疗是胃食管腺癌患者的标准治疗方案,其有效率近40%。尽管铂类药物对癌症患者的疗效不断提高,但是它的毒副作用和耐
1 Source Fareed KR, Al-Attar A, Soomro IN, et al. Rate regression and ERCC1 nuclear protein expression predict clinical outcome in patients with gastro-oesophageal cancer treated with neoadjuvant chemotherapy [J]. Br J Cancer, 2010, 102 11): 1600-1607.2 Level of Evidence 1a. 3 Background Gastro-esophageal neoplasia is a common and fatal disease. Platinum-based neoadjuvant chemotherapy is the standard treatment for patients with gastroesophageal adenocarcinoma with an efficiency of nearly 40%. Although the efficacy of platinum drugs in cancer patients continues to increase, but its side effects and tolerance