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过去人们多注重导尿管材料与尿道炎症的关系,实验研究已发现导尿管引起的尿道炎症与尿管材料的化学成分有关。导尿管所释放的一些物质可能触发周围神经系统活动。近期研究表明尿道粘膜感觉和自主性神经分布与炎症反应有密切关系。作者进一步详细地研究自主性神经系统在导尿管引起的尿道炎症发病过程中的作用。材料和方法:选用SD大鼠,将1mm宽的乳胶导尿管条插入尿道。为了研究自主性神经系统对尿道炎症的影响,分别对实验组大鼠给予胍乙啶、利血平。为进一步观察交感神经系统的影响作用。选择自发性高血压大鼠(SH)具有高的交感神经活性,并选择
In the past, people pay more attention to the relationship between urethral catheterization and urethral inflammation. Experimental studies have found that urethral inflammation caused by catheter is related to the chemical composition of the catheter. Some of the substance released by the catheter may trigger peripheral nervous system activity. Recent studies have shown that the urethral mucosal sensory and autonomic nervous distribution and inflammation are closely related. The authors study in more detail the role of autonomic nervous system in the pathogenesis of urethral inflammation caused by catheterization. MATERIALS AND METHODS: SD rats were used to insert a 1 mm wide latex catheter strip into the urethra. In order to study the influence of autonomic nervous system on urethral inflammation, guinea-bide and reserpine were given to the experimental rats respectively. To further observe the impact of the sympathetic nervous system. Select spontaneous hypertensive rats (SH) have high sympathetic activity and select