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目的探讨甲氨蝶呤联合米非司酮治疗异位妊娠的疗效观察。方法收集2011年8月至2014年8月在我院进行治疗的134例异位妊娠患者资料,将患者完全随机分为试验组和对照组,各67例,试验组患者给予甲氨蝶呤联合米非司酮对患者进行综合治疗,对照组则单独使用米非司酮进行治疗。比较两组患者的治疗效果。结果试验组患者治疗总有效率及血β-绒毛膜促性腺激素(β-HCG)均明显高于对照组,差异均有统计学意义(均P<0.05)。结论利用甲氨蝶呤联合米非司酮综合治疗异位妊娠比单独使用米非司酮进行治疗效果更好,不良反应低,且有效率高。
Objective To investigate the efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods The data of 134 cases of ectopic pregnancy treated in our hospital from August 2011 to August 2014 were collected. The patients were randomly divided into experimental group and control group, with 67 cases in each group. Methotrexate group Mifepristone patients with comprehensive treatment, the control group was treated with mifepristone alone. The treatment effect of two groups of patients was compared. Results The total effective rate of treatment and blood β-HCG in the experimental group were significantly higher than those in the control group (all P <0.05). Conclusion The combination of methotrexate and mifepristone in the treatment of ectopic pregnancy is better than mifepristone alone, with low adverse reactions and high efficiency.